Are you getting burned out on gay guys’ tendency to shave their heads bald once the condition starts showing up naturally? Well, Yale researchers have discovered the source of signals that trigger hair growth, an insight that may lead to new treatments for baldness.
The researchers identified stem cells within the skin’s fatty layer and showed that molecular signals from these cells were necessary to spur hair growth in mice, according to research published in the September 2 issue of the journal Cell.
“If we can get these fat cells in the skin to talk to the dormant stem cells at the base of hair follicles, we might be able to get hair to grow again,” says Valerie Horsley, assistant professor of molecular, cellular, and developmental biology and senior author of the paper.
Men with male-pattern baldness still have stem cells in follicle roots but these stem cells lose the ability to jump-start hair regeneration. Scientists have known that these follicle stem cells need signals from within the skin to grow hair, but the source of those signals has been unclear.
Horsley’s team observed that when hair dies, the layer of fat in the scalp that makes up most of the skin’s thickness shrinks. When hair growth begins, the fat layer expands in a process called adipogenesis. Researchers found that a type of stem cell involved in creation of new fat cells — adipose precursor cells — was required for hair regeneration in mice. They also found these cells produce molecules called platelet-derived growth factors, which are necessary to produce hair growth.
Horsley’s lab is trying to identify other signals produced by adipose precursor stem cells that may play a role in regulating hair growth. She also wants to know whether these same signals are required for human hair growth.
For decades the explanation for Americans’ excessive weight gain has been set fairly straightforward: calories in versus calories out.
But some researchers held that the cause had to be more than just calories. We know that hormones — the chemical messengers produced by our endocrine system to control things like blood pressure and insulin production — can fatten up animals for slaughter; that some drugs increase your weight; and that a change in hormones at midlife shifts where your fat is distributed.
Now some scientists are saying that exposure to those chemicals can damage the body’s natural weight-control mechanisms. And some of those chemicals, they say, could be coming from everyday products that you use without thinking twice about during your daily ritual.
Antiperspirant has been a poor little whipping boy for decades. Do many brands contain ingredients that can lead to Alzheimer’s or cancer — or do they not? The fear factor has risen so high that some people have given up the use of the sweat and odor blockers altogether, or they’ve opted for some kind of alternative treatment or “clean” versions.
The editors of GOOD have given us a breakdown on the suspect ingredients, why they’re potentially bad for our health, and some alternative options.
A poster series for the upcoming Broadway Bares event has been released and gets a review in The New York Times Arts Beat.
An annual AIDS fund-raising event, Broadway Bares will be Sunday, June 19, at the Roseland Ballroom, 239 W. 52nd St., in Manhattan.
You know the old saying, guys: “Beauty is pain.” And let’s face it, behind the scenes — the steps it takes to create beauty — things can be downright ugly.
But whatever a guy can do to keep his man from tasting ear wax when he’s getting amorous with those little licks, flicks, and nibbles on your ear…well, man-up, and get the job down.